{"product_id":"genomics-iii-methods-techniques-and-applications-paperback","title":"Genomics III: Methods, Techniques and Applications - Paperback","description":"\u003cdiv\u003e\u003cp style=\"text-align: right;\"\u003e\u003ca href=\"https:\/\/reportcopyrightinfringement.com\/\" target=\"_blank\" rel=\"nofollow\"\u003e\u003cb\u003eReport copyright infringement\u003c\/b\u003e\u003c\/a\u003e\u003c\/p\u003e\u003c\/div\u003e\u003cp\u003eby \u003cb\u003eIconcept Press\u003c\/b\u003e (Author)\u003c\/p\u003e\u003cp\u003eGenomics is the study of the genomes of organisms. The field includes intensive efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping efforts. It is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyse the function and structure of genomes. Genomics III - Methods, Techniques and Applications is the last volume of our Genomics series. \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e Chapter 1 presents an overview of exome sequencing technology and details its use in identification of molecular bases of rare diseases in human. \u003cp\u003e\u003c\/p\u003e Chapter 2 describes and compares different methods of whole genome amplification (WGA) for replenishing DNA samples for genetic studies. \u003cp\u003e\u003c\/p\u003e Chapter 3 ilustrates the method of whole genome microarray gene expression profiling and its application to study the treatment effect of a widely used cardiovascular drug. \u003cp\u003e\u003c\/p\u003e Chapter 4 describes a brief history of large-insert libraries and their utility in exploring organisms with poor genetic and genome information. \u003cp\u003e\u003c\/p\u003e Chapter 5 proposes a bio-molecular approach for the evaluation of the anaerobic digestion performance. \u003cp\u003e\u003c\/p\u003e In Chapter 6, quantitative issues of the transposon-based gene delivery methods are addressed. Using the \u003ci\u003eSleeping Beauty\u003c\/i\u003e transposon system as a prominent example, special detailed focus is given to copy number determination and to transposon excision efficiency quantification by real-time PCR based methodologies. \u003cp\u003e\u003c\/p\u003e Chapter 7 provides an overview of extraction of a compendium of sequence and structural features, as well as the methodology for function prediction based on the techniques from Artificial Intelligence and Machine learning. \u003cp\u003e\u003c\/p\u003e Chapter 8 presents a statistical method and a data mining solution for the problem of insertion site analysis and characterization of Alu elements \u003cp\u003e\u003c\/p\u003e Chapter 9 investigates how Mutual Information (MI) can be used to improve methods of predicting functional residues and enhance structural data to describe the topological properties of amino acid coevolution networks within a protein and their interactions. \u003cp\u003e\u003c\/p\u003e Chapter 10 attempts to validate MLVA to see if it could predict MRSA clones that were previously characterized by PFGE, MLST, and staphylococcal cassette chromosome mec (SCCmec) typing and to establish possible criteria of clustering MLVA patterns, looking for high concordance levels. \u003cp\u003e\u003c\/p\u003e Chapter 11 introduces a web server which allows the user to perform genome rearrangement analysis using reversals, block-interchanges (also called generalized transpositions) and translocations (including fusions and fissions). \u003cp\u003e\u003c\/p\u003e Chapter 12 discussed an algorithm which is used to optimally align simple sequence repeat (microsatellite) regions as they evolve uniquely through a process called polymerase slippage. \u003cp\u003e\u003c\/p\u003e Chapter 13 possesses a background of the RUN domain research with an emphasis on the interaction between RUN domain protein including RUFY proteins and small GTPases with respect to the cell polarity and membrane trafficking. \u003cp\u003e\u003c\/p\u003e In Chapter 14, the authors detail recent advances in understanding mechanisms of gene regulation in Drosophila.\u003cbr\u003e Chapter 15 provides guidelines for human molecular geneticists to perform genetic screenings using next generation sequencing. \u003cp\u003e\u003c\/p\u003e Chapter 16 describes the process that was used to locate and characterize small group I introns in the rRNA gene locus of fungi. \u003cp\u003e\u003c\/p\u003e Chapter 17 summarizes recent insights in the biology of variant gene transcription in human and murine malaria species and addresses the molecular mechanisms at work which regulate the expression of important virulence factors.\n            \u003cdiv\u003e\n\u003cstrong\u003eNumber of Pages:\u003c\/strong\u003e 374\u003c\/div\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003eDimensions:\u003c\/strong\u003e 1.1 x 9.9 x 7.9 IN\u003c\/div\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003ePublication Date:\u003c\/strong\u003e March 20, 2014\u003c\/div\u003e\n            ","brand":"BooksCloud","offers":[{"title":"Default Title","offer_id":48266348658937,"sku":"9781922227416","price":120.15,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0789\/2782\/3097\/files\/mAQGXO818d9781922227416.webp?v=1775672607","url":"https:\/\/bookscloud.io\/products\/genomics-iii-methods-techniques-and-applications-paperback","provider":"BooksCloud Book Dropshipping","version":"1.0","type":"link"}