{"product_id":"high-throughput-screening-methods-and-protocols-paperback-1","title":"High Throughput Screening: Methods and Protocols - Paperback","description":"\u003cdiv\u003e\u003cp style=\"text-align: right;\"\u003e\u003ca href=\"https:\/\/reportcopyrightinfringement.com\/\" target=\"_blank\" rel=\"nofollow\"\u003e\u003cb\u003eReport copyright infringement\u003c\/b\u003e\u003c\/a\u003e\u003c\/p\u003e\u003c\/div\u003e\u003cp\u003eby \u003cb\u003eWilliam P. Janzen\u003c\/b\u003e (Editor)\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cb\u003e1. Design and Implementation of High Throughput Screening Assays\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eDavid J. Powell, Robert P. Hertsberg, and Ricardo Macarrόn\u003cbr\u003e\u003c\/i\u003e\u003cb\u003e\u003cbr\u003e2. Characterization of Inhibitor Binding Through Multiple Inhibitor Analysis: A Novel Local Fitting Method\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eThomas V. Riera, Tim J. Wigle, and Robert A. Copeland \u003c\/i\u003e\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e3. High Throughput Screening Using Mass Spectrometry within Drug Discovery\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eMattias Rohman and Jonathan Wingfield \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e4. Structure-Based Virtual Screening of Commercially Available Compound Libraries\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eDmitri Kireev \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e5. AlphaScreen-Based Assays: Ultra-High Throughput Screening for Small Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eAdam Yasgar, Ajit Jadhav, Anton Simeonov, and Nathan P. Coussens \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e6. Instrument Quality Control\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eChatura Jayakody and Emily A. Hull-Ryde \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e7. Application of Fluorescence Polarization in HTS Assays\u003ci\u003eXinyi Huang and Ann Aulabaugh \u003c\/i\u003e\u003c\/b\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e8. Time Resolved Fluorescence Assays\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eChen-Ting Ma and Eduard A. Sergienko \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e9. Protein Kinase Selectivity Profiling Using Microfluid Mobility Shift Assays\u003cbr\u003e \u003c\/b\u003e\u003ci\u003ePeter Drueckes \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e10. Screening for Inhibitors of Kinase Autophosphorylation\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eBianca Heedmann and Martin Klumpp \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e11. A Fluorescence-Based High Throughput Screening Assay to Identify Growth Inhibitors of the Pathogenic Fungus \u003ci\u003eAspergillus fumigatus\u003c\/i\u003e\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eThomas M. Smith, Daryl L. Richie, Jianshi Tao \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e12. \u003ci\u003eMycobacterium tuberculosis\u003c\/i\u003e\u003c\/b\u003e\u003ci\u003e \u003c\/i\u003e\u003cb\u003eHigh Throughput Screening\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eE. Lucile White, Nichole A. Tower, and Lynn Rasmussen \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e13. Identification of State-Dependent Blockers for Voltage Gated Calcium Channels Using a FLIPR Based Assay\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eAlberto di Silvio \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e14. A Luciferase Reporter Gene System for High Throughput Screening of \u003c\/b\u003e\u003cb\u003eγ-Globin\u003c\/b\u003e\u003ci\u003e \u003c\/i\u003e\u003cb\u003eGene Activators\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eWensheng Xie, Robert Silvers, Michael Ouellette, Zining Wu, Quinn Lu, Hu Li, Kathleen Gallagher, Kathy Johnson, and Monica Montoute \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e15. A High Throughput Flow Cytometry Assay for Identification of Inhibitors of 3', 5'-Cyclic Adenosine Monophosphate Efflux\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eDominique Perez, Peter C. Simons, Yelena Smagley, Larry A. Sklar, and Alexandre Chigaev \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e16. High Throughput Cell Toxicity Assays\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eDavid Murray, Lisa McWilliams, and Mark Wigglesworth \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e17. BRET\u003csup\u003en\u003c\/sup\u003e: NanoLuc-Based Bioluminescence Resonance Energy Transfer Platform to Monitor Protein-Protein Interactions in Live Cells\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eXiu-Lei Mo and Haian Fu \u003c\/i\u003e\u003cp\u003e\u003c\/p\u003e \u003cb\u003e18. Application of Imaging-Based Assays in Microplate Formats for High Content Screening\u003cbr\u003e \u003c\/b\u003e\u003ci\u003eAdam I. Fogel, Scott E. Martin, and Samuel A. Hasson\u003cbr\u003e\u003c\/i\u003e\u003ch3\u003eBack Jacket\u003c\/h3\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003eThis third edition volume expands on the previous editions both by presenting more detailed protocols for the techniques described in the first and second editions of \u003ci\u003eHigh Throughput Screening: Methods and Protocols\u003c\/i\u003e and by covering important new procedures\u003ci\u003e.\u003c\/i\u003e The first chapter of this book provides an overview of important assay development techniques, while the rest of the chapters detail how to develop and execute screens at whatever throughput the user needs. Some chapter examples are: structure-based virtual screening, high throughput screening using mass spectrometry, identification of state-dependent blockers for voltage gated calcium channels, bioluminescence resonance energy transfer platform to monitor protein-protein interactions in live cells, high throughput flow cytometry, and application of imaging-based assays in microplate formats for high content screening. Written in the highly successful \u003ci\u003eMethods in Molecular Biology \u003c\/i\u003eseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. \u003c\/p\u003e\u003cp\u003e\u003c\/p\u003eCutting edge and thorough, \u003ci\u003eHigh Throughput Screening: Methods and Protocols, Third Edition, \u003c\/i\u003eis a valuable resource for anyone who is interested in HTS research.\n            \u003cdiv\u003e\n\u003cstrong\u003eNumber of Pages:\u003c\/strong\u003e 308\u003c\/div\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003eDimensions:\u003c\/strong\u003e 0.67 x 10 x 7 IN\u003c\/div\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003eIllustrated:\u003c\/strong\u003e Yes\u003c\/div\u003e\n            \u003cdiv\u003e\n\u003cstrong\u003ePublication Date:\u003c\/strong\u003e May 31, 2018\u003c\/div\u003e\n            ","brand":"BooksCloud","offers":[{"title":"Default Title","offer_id":47380032159993,"sku":"9781493981137","price":192.78,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0789\/2782\/3097\/files\/dkJFVFZ5RWZqWENiaVg1VU1HYTRydz09_c372cf59-45a4-4975-9290-5d1a0f8a9651.webp?v=1770060054","url":"https:\/\/bookscloud.io\/products\/high-throughput-screening-methods-and-protocols-paperback-1","provider":"BooksCloud Book Dropshipping","version":"1.0","type":"link"}